The MRI appearances of early vertebral osteomyelitis and discitis
Received 4 November 2009; received in revised form 5 March 2010; accepted 15 March 2010. published online 08 July 2010. Corrected Proof
Aim
To describe the magnetic resonance imaging (MRI) appearances in patients with a clinical history suggestive of vertebral osteomyelitis and discitis who underwent MRI very early in their clinical course.
Materials and methods
A retrospective review of the database of spinal infections from a spinal microbiological liaison team was performed over a 2 year period to identify cases with clinical features suggestive of spinal infection and an MRI that did not show features typical of vertebral osteomyelitis and discitis. All patients had positive microbiology and a follow up MRI showing typical features of spinal infection.
Results
In four cases the features typical of spinal infection were not evident at the initial MRI. In three cases there was very subtle endplate oedema associated with disc degeneration, which was interpreted as Modic type I degenerative endplate change. Intravenous antibiotic therapy was continued prior to repeat MRI examinations. The mean time to the repeat examination was 17 days with a range of 8–22 days. The second examinations clearly demonstrated vertebral osteomyelitis and discitis.
Conclusion
Although MRI is the imaging method of choice for vertebral osteomyelitis and discitis in the early stages, it may show subtle, non-specific endplate subchondral changes; a repeat examination may be required to show the typical features.
aDepartment of Microbiology, Leeds General Infirmary, Leeds LS1 3EX, UK
bDepartment of Orthopaedics, Leeds General Infirmary, Leeds LS1 3EX, UK
cDepartment of Neurosurgery, Leeds General Infirmary, Leeds LS1 3EX, UK
dDepartment of Cardiology, Leeds General Infirmary, Leeds LS1 3EX, UK
eDepartment of Radiology, Leeds General Infirmary, Leeds LS1 3EX, UK
fLeeds Musculoskeletal Biomedical Research Unit, Leeds, UK
Guarantor and correspondent: J.J. Rankine, Department of Radiology, Leeds General Infirmary, Leeds LS1 3EX, UK. Tel.: +44 113 392 3768; fax: +44 113 392 8241.
ABSTRACT