Clinical Radiology
Volume 65, Issue 8 , Pages 601-608 , August 2010

Coronary heart disease risk assessment and characterization of coronary artery disease using coronary CT angiography: comparison of asymptomatic and symptomatic groups

  • Y. Hwang

      Affiliations

    • Department of Radiology, School of Medicine, Ewha Womans University, Seoul, Republic of Korea
  • ,
  • Y. Kim

      Affiliations

    • Department of Radiology, School of Medicine, Ewha Womans University, Seoul, Republic of Korea
    • Corresponding Author InformationGuarantor and correspondent: Y. Kim, Department of Radiology, Ewha Womans University Mokdong Hospital, 911-1, Mokdong, Yancheon-gu, Seoul 158-710, Republic of Korea. Tel.: +82 2 2650 5380; fax: +82 2 2650 5302.
  • ,
  • I.-M. Chung

      Affiliations

    • Division of Cardiology in Department of Internal Medicine, School of Medicine, Ewha Womans University, Seoul, Republic of Korea
  • ,
  • J. Ryu

      Affiliations

    • Department of Preventive Medicine, School of Medicine, Ewha Womans University, Seoul, Republic of Korea
  • ,
  • H. Park

      Affiliations

    • Department of Preventive Medicine, School of Medicine, Ewha Womans University, Seoul, Republic of Korea

Received 2 November 2009 ,Revised 1 April 2010 ,Accepted 7 April 2010.

References 

  1. National Cholesterol Education Program (NCEP) Expert Panel on Detection . Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation. 2002;106:3143–3421
  2. Johnson KM, Dowe DA, Brink JA. Traditional clinical risk assessment tools do not accurately predict coronary atherosclerotic plaque burden: a CT angiography study. AJR Am J Roentgenol. 2009;192:235–243
  3. Akosah KO, Schaper A, Cogbill C, et al. Preventing myocardial infarction in the young adult in the first place: how do the National Cholesterol Education Panel III guidelines perform?. J Am Coll Cardiol. 2003;41:1475–1479
  4. Nasir K, Michos ED, Blumenthal RS, et al. Detection of high-risk young adults and women by coronary calcium and National Cholesterol Education Program Panel III guidelines. J Am Coll Cardiol. 2005;46:1931–1936
  5. Pugliese F, Mollet NR, Hunink MG, et al. Diagnostic performance of coronary CT angiography by using different generations of multisection scanners: single-center experience. Radiology. 2008;246:384–393
  6. Hamon M, Morello R, Riddell JW, et al. Coronary arteries: diagnostic performance of 16- versus 64-section spiral CT compared with invasive coronary angiography—meta-analysis. Radiology. 2007;245:720–731
  7. Einstein AJ, Henzlova MJ, Rajagopalan S. Estimating risk of cancer associated with radiation exposure from 64-slice computed tomography coronary angiography. JAMA. 2007;298:317–323
  8. Hausleiter J, Meyer T, Hadamitzky M, et al. Prevalence of noncalcified coronary plaques by 64-slice computed tomography in patients with an intermediate risk for significant coronary artery disease. J Am Coll Cardiol. 2006;48:312–318
  9. Diamond GA, Forrester JS. Analysis of probability as an aid in the clinical diagnosis of coronary-artery disease. N Engl J Med. 1979;300:1350–1358
  10. Agatston AS, Janowitz WR, Hildner FJ, et al. Quantification of coronary artery calcium using ultrafast computed tomography. J Am Coll Cardiol. 1990;15:827–832
  11. Cooney MT, Dudina AL, Graham IM. Value and limitations of existing scores for the assessment of cardiovascular risk: a review for clinicians. J Am Coll Cardiol. 2009;54:1209–1227
  12. Berger JS, Jordan CO, Lloyd-Jones D, et al. Screening for cardiovascular risk in asymptomatic patients. J Am Coll Cardiol. 2010;55:1169–1177
  13. Cademartiri F, Romano M, Seitun S, et al. Prevalence and characteristics of coronary artery disease in a population with suspected ischemic heart disease using CT coronary angiography: correlations with cardiovascular risk factors and clinical presentation. Radiol Med. 2008;113:363–372
  14. Rumberger JA, Simons DB, Fitzpatrick LA, et al. Coronary artery calcium area by electron-beam computed tomography and coronary atherosclerotic plaque area. A histopathologic correlative study. Circulation. 1995;92:2157–2162
  15. Detrano R, Guerci AD, Carr JJ, et al. Coronary calcium as a predictor of coronary events in four racial or ethnic groups. N Engl J Med. 2008;358:1336–1345
  16. Alderman EL, Corley SD, Fisher LD, et al. Five-year angiographic follow-up of factors associated with progression of coronary artery disease in the Coronary Artery Surgery Study (CASS). CASS participating investigators and staff. J Am Coll Cardiol. 1993;22:1141–1154
  17. Haberl R, Becker A, Leber A, et al. Correlation of coronary calcification and angiographically documented stenoses in patients with suspected coronary artery disease: results of 1,764 patients. J Am Coll Cardiol. 2001;37:451–457
  18. Raggi P, Callister TQ, Cooil B, et al. Identification of patients at increased risk of first unheralded acute myocardial infarction by electron-beam computed tomography. Circulation. 2000;101:850–855
  19. Choi EK, Choi SI, Rivera JJ, et al. Coronary computed tomography angiography as a screening tool for the detection of occult coronary artery disease in asymptomatic individuals. J Am Coll Cardiol. 2008;52:357–365
  20. Falk E, Shah PK, Fuster V. Coronary plaque disruption. Circulation. 1995;92:657–671
  21. Feuchtner G, Postel T, Weidinger F, et al. Is there a relation between non-calcifying coronary plaques and acute coronary syndromes? A retrospective study using multislice computed tomography. Cardiology. 2008;110:241–248
  22. Bachar GN, Atar E, Fuchs S, et al. Prevalence and clinical predictors of atherosclerotic coronary artery disease in asymptomatic patients undergoing coronary multidetector computed tomography. Coron Artery Dis. 2007;18:353–360
  23. Romeo F, Leo R, Clementi F, et al. Multislice computed tomography in an asymptomatic high-risk population. Am J Cardiol. 2007;99:325–328
  24. Achenbach S, Marwan M, Ropers D, et al. Coronary computed tomography angiography with a consistent dose below 1 mSv using prospectively electrocardiogram-triggered high-pitch spiral acquisition. Eur Heart J. 2010;31:340–346
  25. Lell M, Marwan M, Schepis T, et al. Prospectively ECG-triggered high-pitch spiral acquisition for coronary CT angiography using dual source CT: technique and initial experience. Eur Radiol. 2009;19:2576–2583

PII: S0009-9260(10)00188-1

doi: 10.1016/j.crad.2010.04.009

Clinical Radiology
Volume 65, Issue 8 , Pages 601-608 , August 2010