Clinical Radiology
Volume 65, Issue 5 , Pages 391-394 , May 2010

Choice of echo time on GRE T2*-weighted MRI influences the classification of brain microbleeds

  • S.M. Gregoire

      Affiliations

    • Stroke Research Group, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, London WC1N 3BG, UK
    • ,
  • D.J. Werring

      Affiliations

    • Stroke Research Group, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, London WC1N 3BG, UK
    • Corresponding Author InformationGuarantor and correspondent: D.J. Werring, Stroke Research Group, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, London WC1N 3BG, UK. Tel.: +44 2078298753; fax: +44 2078338613.
    • ,
  • U.J. Chaudhary

      Affiliations

    • Stroke Research Group, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, London WC1N 3BG, UK
    • ,
  • J.S. Thornton

      Affiliations

    • Lysholm Department of Neuroradiology, UCL Institute of Neurology and National Hospital for Neurology and Neurosurgery, London, UK
    • ,
  • M.M. Brown

      Affiliations

    • Stroke Research Group, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, London WC1N 3BG, UK
    • ,
  • T.A. Yousry

      Affiliations

    • Lysholm Department of Neuroradiology, UCL Institute of Neurology and National Hospital for Neurology and Neurosurgery, London, UK
    • ,
  • H.R. Jäger

      Affiliations

    • Lysholm Department of Neuroradiology, UCL Institute of Neurology and National Hospital for Neurology and Neurosurgery, London, UK

,Revised 23 December 2009 ,Accepted 5 January 2010.

References 

  1. Cordonnier C, Al-Shahi Salman R, Wardlaw J. Spontaneous brain microbleeds: systematic review, subgroup analyses and standards for study design and reporting. Brain. 2007;130:1988–2003
  2. Werring DJ, Frazer DW, Coward LJ, et al. Cognitive dysfunction in patients with cerebral microbleeds on T2*-weighted gradient-echo MRI. Brain. 2004;127:2265–2275
  3. Greenberg SM, Vernooij MW, Cordonnier C, et al. Cerebral microbleeds: a guide to detection and interpretation. Lancet Neurol. 2009;8:165–174
  4. Cordonnier C, Potter GM, Jackson CA, et al. Improving interrater agreement about brain microbleeds. Development of the brain observer microbleed scale (BOMBS). Stroke. 2009;40:94–99
  5. Sveinbjornsdottir S, Sigurdsson S, Aspelund T, et al. Cerebral microbleeds in the population based AGES Reykjavik study: prevalence and location. J Neurol Neurosurg Psychiatry. 2008;79:1002–1006
  6. Tatsumi S, Ayaki T, Shinohara M, et al. Type of gradient recalled-echo sequence results in size and number change of cerebral microbleeds. AJNR Am J Neuroradiol. 2008;29:13
  7. Gregoire SM, Chaudhary UJ, Brown MM, et al. The microbleed anatomical rating scale (MARS): a new reliable tool to map brain microbleeds. Neurology. 2009;73:1759–1766
  8. Vernooij MW, Ikram MA, Wielopolski PA, et al. Cerebral microbleeds: accelerated 3D T2*-weighted GRE MR imaging versus conventional 2D T2*-weighted GRE MR imaging for detection. Radiology. 2008;248:272–277
  9. Scheid R, Ott DV, Roth H, et al. Comparative magnetic resonance imaging at 1.5 and 3 Tesla for the evaluation of traumatic microbleeds. J Neurotrauma. 2007;24:1811–1816
  10. Nandigam RNK, Viswanathan A, Delgado P, et al. MR imaging detection of cerebral microbleeds: effect of susceptibility-weighted imaging, section thickness, and field strength. AJNR Am J Neuroradiol. 2009;30:338–343

PII: S0009-9260(10)00032-2

doi: 10.1016/j.crad.2010.01.004

Clinical Radiology
Volume 65, Issue 5 , Pages 391-394 , May 2010

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