Clinical Radiology
Volume 65, Issue 2 , Pages 137-144 , February 2010

Does computer-assisted detection of pulmonary emboli enhance severity assessment and risk stratification in acute pulmonary embolism?

  • C. Engelke

      Affiliations

    • Department of Radiology, University Hospital Goettingen, 37075 Goettingen, Germany
    • Corresponding Author InformationGuarantor and correspondent: Department of Radiology, University Hospital Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany. Tel.: +49 551 398965; fax: +49 551 399606.
  • ,
  • S. Schmidt

      Affiliations

    • Department of Radiology, Klinikum rechts der Isar, Technical University Munich, Germany
  • ,
  • F. Auer

      Affiliations

    • Department of Radiology, Klinikum rechts der Isar, Technical University Munich, Germany
  • ,
  • E.J. Rummeny

      Affiliations

    • Department of Radiology, Klinikum rechts der Isar, Technical University Munich, Germany
  • ,
  • K. Marten

      Affiliations

    • Department of Radiology, University Hospital Goettingen, 37075 Goettingen, Germany

Received 15 July 2008 ,Revised 6 October 2009 ,Accepted 16 October 2009.

References 

  1. Collomb D, Paramelle PJ, Calaque O, et al. Severity assessment of acute pulmonary embolism: evaluation using helical CT. Eur Radiol. 2003;13:1508–1514
  2. Qanadli SD, Hajjam ME, Vieillard-Baron A, et al. New CT index to quantify arterial obstruction in pulmonary embolism: comparison with angiographic index of echocardiography. AJR Am J Roentgenol. 2001;176:1415–1420
  3. Bankier AA, Janata K, Fleischmann D, et al. Severity assessment of acute pulmonary embolism with spiral CT: evaluation of two modified angiographic scores and comparison with clinical data. J Thorac Imaging. 1997;12:150–158
  4. Mastora I, Remy-Jardin M, Masson P, et al. Severity of acute pulmonary embolism: evaluation of a new spiral CT angiographic score in correlation with echocardiographic data. Eur Radiol. 2003;13:29–35
  5. Engelke C, Rummeny EJ, Marten K. Acute pulmonary embolism on multidetector-row CT of the chest: prediction of cor pulmonale and short-term patient survival from morphological embolus burden. AJR Am J Roentgenol. 2006;186:1265–1271
  6. Wu AS, Pezzullo JA, Cronan JJ, et al. CT pulmonary angiography: quantification of pulmonary embolus as a predictor of patient outcome—initial experience. Radiology. 2004;230:831–835
  7. Araoz PA, Gotway MB, Trowbridge RL, et al. Helical CT pulmonary angiography predictors of in-hospital morbidity and mortality in patients with acute pulmonary embolism. J Thorac Imaging. 2003;18:207–216
  8. Engelke C, Marten K. Multidetector-row CT in severe pulmonary embolism: radiologists' help in risk stratification. [In German] Radiologe. 2007;47:725–734quiz 735–736
  9. Engelke C, Schmidt S, Bakai A, et al. Computer-assisted detection of pulmonary embolism: performance evaluation in consensus with experienced and inexperienced chest radiologists. Eur Radiol. 2007;Sep 28 [Epub ahead of print]
  10. Engelke C, Rummeny EJ, Marten K. Missed and incidental pulmonary embolism on multislice CT of the chest: one-year follow-up of treated and untreated patients. Radiology. 2006;239:563–575
  11. Liang J, Bi J. Computer aided detection of pulmonary embolism with tobogganing and multiple instance classification in CT pulmonary angiography. Inf Process Med Imaging. 2007;20:630–641
  12. Ghaye B, Szapiro D, Mastora I, et al. Peripheral pulmonary arteries: how far in the lung does multi-detector row spiral CT allow analysis?. Radiology. 2001;219:629–636
  13. Remy-Jardin M, Remy J, Petyt L, et al. Diagnosis of acute pulmonary embolism with spiral CT: comparison with pulmonary angiography and scintigraphy. Radiology. 1996;200:699–706
  14. Bland M, Altman DG. Statistical methods for assessing the difference between two methods of measurement. Lancet. 1986;i:307–310
  15. Fleiss JL, Nee CM, Landis JR. Large sample variance of kappa in the case of different sets of raters. Psychol Bull. 1979;86:974–977
  16. Marten K, Grillhösl A, Seyfarth T, et al. Computer-assisted detection of pulmonary nodules: evaluation of diagnostic performance using an expert knowledge-based detection system with variable reconstruction slice thickness settings. Eur Radiol. 2005;15:203–212
  17. Croisille P, Souto M, Cova M, et al. Pulmonary nodules: improved detection with vascular segmentation and extraction with spiral CT. Radiology. 1995;197:397–401
  18. Wormanns D, Fiebich M, Saidi M, et al. Automatic detection of pulmonary nodules at spiral CT: clinical application of a computer-aided diagnosis system. Eur Radiol. 2002;12:1052–1057
  19. Marten K, Engelke C. Computer-aided detection and automated CT volumetry of pulmonary nodules. European Radiology. 2007;17:888–901
  20. Armato SG, Giger ML, Moran CJ, et al. Computerized detection of pulmonary nodules on CT scans. RadioGraphics. 1999;19:1303–1311
  21. Armato SG, Li F, Giger ML, et al. Lung cancer: performance of automated lung nodule detection applied to cancers missed in a CT screening program. Radiology. 2002;225:685–692
  22. Rubin G, Naidich D, Sherbondy A, et al. Inadequacy of lung nodule reference standard based upon standard methods of expert consensus review using cine-paging of transverse thin-section MDCT lung scans. Radiology. 2003;229:441–442
  23. Marten K, Seyfarth T, Auer F, et al. Computer-assisted detection of pulmonary nodules: performance evaluation of an expert knowledge-based detection system in consensus reading with experienced and inexperienced chest radiologists. Eur Radiol. 2004;14:1930–1938
  24. Schoepf UJ, Schneider AC, Das M, et al. Pulmonary embolism: computer-aided detection at multidetector row spiral computed tomography. J Thorac Imaging. 2007;22:319–323
  25. Das M, Mühlenbach G, Helm A, et al. Computer-aided detection of pulmonary embolism: influence on radiologists' detection performance with respect to vessel segments. Eur Radiol. 2008;feb 22 [Epub ahead of print]
  26. White CS. Computer-assisted detection for pulmonary embolism on MDCT: can CAD help Rad?. J Thor Imag. 2007;22:317–318
  27. Masutani Y, MacMahon H, Doi K. Computerized detection of pulmonary embolism in spiral CT angiography based on volumetric image analysis. IEEE Trans Med Imaging. 2002;21:1517–1523
  28. Zhou C, Chan HP, Patel S, et al. Preliminary investigation of computer-aided detection of pulmonary embolism in three-dimensional computed tomography pulmonary angiography images. Acad Radiol. 2005;12:782–792
  29. Maizlin ZV, Vos PM, Godoy MB, et al. Computer-aided detection of pulmonary embolism on CT angiography: initial experience. J Thorac Imaging. 2007;22:324–329
  30. Buhmann S, Herzog P, Liang J, et al. Clinical evaluation of a computer-aided diagnosis (CAD) prototype for the detection of pulmonary embolism. Acad Radiol. 2007;14:651–658
  31. Schoepf UJ, Das M, Schneider AC, et al. Computer-aided detection (CAD) of segmental and subsegmental pulmonary embolism on 1-mm multidetector-row CT (MDCT) studies. Radiology. 2002;225:384
  32. Schoepf U, Holzknecht M, Helmberger TK, et al. Subsegmental pulmonary emboli improved detection with thin-collimation multi-detector row spiral CT. Radiology. 2002;222:482–490
  33. Diffin D, Leyendecker J, Johnson S, et al. Effect of anatomic distribution of pulmonary emboli on interobserver agreement in the interpretation of pulmonary angiography. AJR Am J Roentgenol. 1998;171:1085–1089
  34. Wood KE. Major pulmonary embolism: review of a pathophysiologic approach to the golden hour of hemodynamically significant pulmonary embolism. Chest. 2002;121:877–905
  35. Dalen J, Alpert J. Natural history of pulmonary embolism. Progr Cardiovasc Dis. 1975;17:257–270
  36. Le Gal G, Righini M, Parent F, et al. Diagnosis and management of subsegmental pulmonary embolism. J. Thromb. Haemost. 2006;4:724–731
  37. Engelke C, Rummeny EJ, Marten K. Acute pulmonary embolism on multidetector-row CT of the chest: prediction of cor pulmonale and short-term patient survival from morphological embolus burden. Eur Radiol. 2006;16:B-589
  38. De Perrot M, Fadel E, Mc Rae K, et al. Evaluation of persistent pulmonary hypertension after acute pulmonary embolism. Chest. 2007;132:780–785
  39. Price D. Pulmonary embolism. Prophylaxis diagnosis and treatment. Anaesthesia. 1976;31:925–932
  40. Egermayer P. Differences in the rate of anticoagulant complications between routine practice and controlled prospective trials. J Intern Med. 2001;250:258–261

PII: S0009-9260(09)00385-7

doi: 10.1016/j.crad.2009.10.007

Clinical Radiology
Volume 65, Issue 2 , Pages 137-144 , February 2010