Clinical Radiology
Volume 64, Issue 12 , Pages 1181-1187 , December 2009

Reliability of the bright liver echo pattern in diagnosing steatosis in patients with cryptogenic and HCV-related hypertransaminasaemia

  • M. Soresi

      Affiliations

    • Clinical Medicine and Emerging Pathologies, University of Palermo, Palermo, Italy
  • ,
  • L. Giannitrapani

      Affiliations

    • Clinical Medicine and Emerging Pathologies, University of Palermo, Palermo, Italy
  • ,
  • A.M. Florena

      Affiliations

    • Department of Human Pathology, University of Palermo, Palermo, Italy
  • ,
  • E. La Spada

      Affiliations

    • Clinical Medicine and Emerging Pathologies, University of Palermo, Palermo, Italy
  • ,
  • V. Di Gesaro

      Affiliations

    • Clinical Medicine and Emerging Pathologies, University of Palermo, Palermo, Italy
  • ,
  • F. Rappa

      Affiliations

    • Department of Human Pathology, University of Palermo, Palermo, Italy
  • ,
  • A. Alessandri

      Affiliations

    • Clinical Medicine and Emerging Pathologies, University of Palermo, Palermo, Italy
  • ,
  • S. Tripi

      Affiliations

    • Clinical Medicine and Emerging Pathologies, University of Palermo, Palermo, Italy
  • ,
  • M. Romano

      Affiliations

    • Unit of Geriatrics, A.R.N.A.S. Garibaldi, Catania, Italy
  • ,
  • G. Montalto

      Affiliations

    • Clinical Medicine and Emerging Pathologies, University of Palermo, Palermo, Italy
    • Corresponding Author InformationGuarantor and correspondent: G. Montalto, Department of Clinical Medicine and Emerging Pathologies, University of Palermo, via del Vespro, 141; 90 127 Palermo, Italy. Tel.: +39 091 6552991; fax: +39 091 6552847.

Received 28 November 2008 ,Revised 20 June 2009 ,Accepted 29 June 2009.

References 

  1. Pendino GM, Mariano A, Surace P, et al. Prevalence and etiology of altered liver tests: a population-based survey in a Mediterranean town. Hepatology. 2005;41:1151–1159
  2. Bellantani S, Tiribelli C, Saccocci D, et al. Prevalence of chronic liver disease in the general population of northern Italy: the Dionysos Study. Hepatology. 1994 Dec;20(6):1442–1449
  3. Lonardo A, Loria P, Adinolfi LE, et al. Hepatitis C and steatosis: a reappraisal. J Viral Hepat. 2006 Feb;13:73–80
  4. Daniel S, Ben-Menachem T, Vasudevan G, et al. Prospective evaluation of unexplained chronic liver transaminase abnormalities in asymptomatic and symptomatic patients. Am J Gastroenterol. 1999;94:3010–3014
  5. Bersain C, Betes M, Panizo A, et al. Pathological and virological findings in patients with persistent hypertransaminasaemia of unknown aetiology. Gut. 2000;47:429–435
  6. Skelly MM, James PD, Ryder SD. Findings of liver biopsy to investigate abnormal liver function tests in the absence of diagnostic serology. J Hepatol. 2001;35:195–199
  7. Sanyal AJ, American Gastroenterological Association . AGA technical review of non-alcoholic fatty liver disease. Gastroenterology. 2002;123:1705–1725
  8. Rinella ME, McCarthy R, Takrar K, et al. Dual-echo, chemical shift gradient-echo magnetic resonance imaging to quantify hepatic steatosis: implications for living liver donation. Liver Transpl. 2003;9:851–856
  9. Joseph AEA, Dewbury KC, Mac Guire PG. Ultrasound in the detection of chronic liver disease (the “bright liver”). Br J Radiol. 1979;53:440–442
  10. Yaijma Y, Oht K, Narui T, et al. Ultrasonographical diagnosis of fatty liver: significance of the liver–kidney contrast. Tohoku J Exp Med. 1983;139:43–50
  11. Taylor KJ, Riely CA, Hammers L, et al. Quantitative US attenuation in normal liver and in patients with diffuse liver disease: importance of fat. Radiology. 1986;160:65–71
  12. Joseph AE, Saverymuttu SH, al–Sam S, et al. Comparison of liver histology with ultrasonography in assessing diffuse parenchymal liver disease. Clin Radiol. 1991;43:26–31
  13. Sanford NL, Walsh P, Matis C, et al. Is ultrasonography useful in the assessment of diffuse parenchymal liver disease?. Gastroenterology. 1985;89:186–191
  14. Saadeh S, Younossi ZM, Remer EM, et al. The utility of radiological imaging in non-alcoholic fatty liver disease. Gastroenterology. 2002;123:745–750
  15. Mathiesen UL, Franzen LE, Aselius H, et al. Increased liver echogenicity at ultrasound examination reflects degree of steatosis but not of fibrosis in asymptomatic patients with mild/moderate abnormalities of liver transaminases. Dig Liver Dis. 2002;34:516–522
  16. Hepburn MJ, Vos JA, Fillman EP, et al. The accuracy of the report of hepatic steatosis on ultrasonography in patients infected with hepatitis C in a clinical setting: a retrospective observational study. BMC Gastroenterol. 2005;13:5–14
  17. Palmentieri B, De Sio I, La Mura V, et al. The role of bright liver echopattern on ultrasound B-mode examination in the diagnosis of liver steatosis. Dig Liver Dis. 2006;38:485–489
  18. Hamaguchi M, Kojima T, Itoh Y, et al. The severity of ultrasonographic findings in nonalcoholic fatty liver disease reflects the metabolic syndrome and visceral fat accumulation. Am J Gastroenterol. 2007;102:2708–2715
  19. Needleman L, Kurtz AB, Rifkin MD, et al. Sonography of diffuse benign liver disease: accuracy of pattern recognition and grading. AJR Am J Roentgenol. 1986;146:1011–1015
  20. Strauss S, Gavish E, Gottlieb P, et al. Interobserver and intraobserver variability in the sonographic assessment of fatty liver. AJR Am J Roentgenol. 2007;189:W320–W323
  21. The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus . Follow-up report on the diagnosis of diabetes mellitus. Diabetes Care. 2003;26:3160–3167
  22. Guidelines Sub-Committee . 1999 World Health Organization–International Society of Hypertension guidelines for the management of hypertension. J Hypertens. 1999;17:151–183GL
  23. Available at: http://www.med.unibo.it/rad2/Rad/Leggi/LINEE_GUIDA_SIUMB_2005.pdf
  24. Scheuer PJ. Classification of chronic viral hepatitis: a need for reassessment. J Hepatol. 1991;13:372–374
  25. Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics. 1977;33:159–174
  26. Cammà C, Bruno S, Di Marco V, et al. Insulin resistance is associated with steatosis in nondiabetic patients with genotype 1 chronic hepatitis C. Hepatology. 2006;43:64–71
  27. Soresi M, Tripi S, Franco V, et al. Impact of liver steatosis on the antiviral response in the hepatitis C virus-associated chronic hepatitis. Liver Int. 2006;26:1119–1125

PII: S0009-9260(09)00296-7

doi: 10.1016/j.crad.2009.06.013

Clinical Radiology
Volume 64, Issue 12 , Pages 1181-1187 , December 2009