Clinical Radiology
Volume 64, Issue 4 , Pages 368-372 , April 2009

Effect of intravenous contrast agent volume on colorectal cancer vascular parameters as measured by perfusion computed tomography

  • V. Goh

      Affiliations

    • Paul Strickland Scanner Centre, Mount Vernon Hospital, Northwood, London, UK
  • ,
  • C. Bartram

      Affiliations

    • Intestinal Imaging Centre, St Mark's Hospital, Harrow, London, UK
  • ,
  • S. Halligan

      Affiliations

    • Department of Academic Radiology, University College Hospital, London, UK
    • Corresponding Author InformationGuarantor and correspondent: S. Halligan, Level 2 Podium, University College Hospital, 235 Euston Road, London NW1 2BU, UK. Tel.: +44 207 380 9010; fax: +44 207 380 9068.

Received 5 May 2008 ,Revised 22 August 2008 ,Accepted 30 August 2008.

References 

  1. Miles KA, Hayball MP, Dixon AK. Functional images of hepatic perfusion obtained by dynamic CT. Radiology. 1993;188:405–411
  2. Blomley MJ, Coulden R, Dawson P, et al. Liver perfusion studied with ultrafast CT. J Comput Assist Tomogr. 1995;19:424–433
  3. Leggett DA, Kelley BB, Bunce IH, et al. Colorectal cancer: diagnostic potential of CT measurements of hepatic perfusion and implications for contrast enhancement protocols. Radiology. 1997;205:716–720
  4. Bader TR, Herneth AM, Blaicher W, et al. Hepatic perfusion after liver transplantation: non-invasive measurement with dynamic single section CT. Radiology. 1998;209:129–134
  5. Van Beers BE, Leconte I, Materne R, et al. Hepatic perfusion parameters in chronic liver disease: dynamic CT measurements correlated with disease severity. AJR Am J Roentgenol. 2001;176:667–673
  6. Miles KA, Hayball MP, Dixon AK. Measurement of human pancreatic perfusion using dynamic computed tomography with perfusion imaging. Br J Radiol. 1995;68:471–475
  7. Bize PE, Platon A, Becker CD, et al. Perfusion measurement in acute pancreatitis using dynamic perfusion MDCT. AJR Am J Roentgenol. 2006;186:114–118
  8. Abe H, Murakami T, Kubota M, et al. Quantitative tissue blood flow evaluation of pancreatic tumor: comparison of xenon CT technique and perfusion CT technique based on deconvolution analysis. Radiat Med. 2005;23:364–370
  9. Harvey C, Blomley MJ, Dawson P. Functional CT imaging of the acute hyperaemic response to radiation therapy of the prostate gland: early experience. J Comput Assist Tomogr. 2001;25:43–49
  10. Henderson E, Milosevic MF, Haider MA, et al. Functional CT imaging of prostate cancer. Phys Med Biol. 2003;48:3085–3100
  11. Jeukens CR, Van den Berg CA, Donker R, et al. Feasibility and measurement precision of 3D quantitative blood flow mapping of the prostate using dynamic contrast-enhanced multi-slice CT. Phys Med Biol. 2006;51:4329–4343
  12. Hermans R, Lambin P, Van der Groten A, et al. Tumoural perfusion as measured by dynamic computed tomography in head and neck carcinoma. Radiother Oncol. 1999;53:105–111
  13. Gandhi D, Hoeffner EG, Carlos RC, et al. Computed tomography perfusion of squamous carcinoma of the upper aerodigestive tract: initial results. J Comput Assist Tomogr. 2003;27:687–693
  14. Bisdas S, Baghi M, Smolarz A, et al. Quantitative measurements of perfusion and permeability of oropharyngeal and oral cavity cancer, recurrent disease, and associated lymph nodes using first-pass contrast-enhanced computed tomography studies. Invest Radiol. 2007;42:172–179
  15. Zhang M, Kono M. Solitary pulmonary nodules: evaluation of blood flow patterns with dynamic CT. Radiology. 1997;205:471–478
  16. Miles KA, Griffiths MR, Fuentes MA. Standardized perfusion value: universal CT contrast enhancement scale that correlates with FDG PET in lung nodules. Radiology. 2001;220:548–553
  17. Kiessling F, Boese J, Corvinus C, et al. Perfusion CT in patients with advanced bronchial carcinoma: a novel chance for characterization and treatment monitoring. Eur Radiol. 2004;14:1226–1233
  18. Sahani DV, Kalva SP, Hamberg LM, et al. Assessing tumor perfusion and treatment response in rectal cancer with multisection CT: initial observations. Radiology. 2005;234:785–792
  19. Bellomi M, Petralia G, Sonzogni A, et al. CT perfusion for the monitoring of neo-adjuvant chemoradiation therapy in rectal carcinoma. Radiology. 2007;244:486–493
  20. Haider MA, Milosevic M, Fyles A, et al. Assessment of the tumor microenvironment in cervix cancer using dynamic contrast enhanced CT, interstitial fluid pressure and oxygen measurements. Int J Radiat Oncol Biol Phys. 2005;62:1100–1107
  21. Hirasawa H, Tsushima Y, Hirasawa S, et al. Perfusion CT of breast carcinoma: arterial perfusion of nonschirrous carcinoma was higher than that of schirrous carcinoma. Acad Radiol. 2007;14:547–552
  22. Dugdale PE, Miles KA, Bunce I, et al. CT measurement of perfusion and permeability within lymphoma masses and its ability to grade, activity, and chemotherapeutic response. J Comput Assist Tomogr. 1999;23:540–547
  23. Liu Y, Bellomi M, Gatti G, et al. Accuracy of computed tomography perfusion in assessing metastatic involvement of enlarged axillary lymph nodes in patients with breast cancer. Breast Cancer Res. 2007;9:R40
  24. Goh V, Padhani AR, Rasheed S. Functional imaging of colorectal cancer angiogenesis. Lancet Oncol. 2007;8:245–255
  25. Wintermark M, Smith WS, Ko NU, et al. Dynamic perfusion CT: optimizing the temporal resolution and contrast volume for calculation of perfusion CT parameters in stroke patients. AJNR Am J Neuroradiol. 2004;25:720–729
  26. Konig M, Bultmann E, Bode-Schnurbus L, et al. Image quality in CT perfusion imaging of the brain. The role of iodine concentration. Eur Radiol. 2007;17:39–47
  27. Miles KA. Perfusion CT for the assessment of tumor vascularity: which protocol?. Br J Radiol. 2003;76:S36–S42
  28. Miles KA, Griffiths MR. Perfusion CT: a worthwhile enhancement?. Br J Radiol. 2003;76:220–231
  29. Goh V, Halligan S, Gharpuray A, et al. Quantitative assessment of colorectal cancer tumor vascular parameters by using perfusion CT: influence of tumor region of interest. Radiology. 2008;247:726–732

PII: S0009-9260(08)00436-4

doi: 10.1016/j.crad.2008.08.018

Clinical Radiology
Volume 64, Issue 4 , Pages 368-372 , April 2009