Clinical Radiology
Volume 64, Issue 2 , Pages 178-183 , February 2009

Prediction of the presence of invasive disease from the measurement of extent of malignant microcalcification on mammography and ductal carcinoma in situ grade at core biopsy

  • E.A.M. O'Flynn

      Affiliations

    • South East London Breast Screening Programme and National Breast Screening Training Centre, Kings College Hospital NHS, London, UK
    • Corresponding Author InformationGuarantor and correspondent: E. O'Flynn, Department of Breast Radiology, Kings College Hospital, Denmark Hill, London SE5 9RS, UK. Tel.: +44 7714 264461; fax: +44 20 3299 4363.
    • ,
  • J.C. Morel

      Affiliations

    • South East London Breast Screening Programme and National Breast Screening Training Centre, Kings College Hospital NHS, London, UK
    • ,
  • J. Gonzalez

      Affiliations

    • Department of Clinical Research Statistics, Kings College Hospital NHS Foundation Trust, London, UK
    • ,
  • N. Dutt

      Affiliations

    • Department of Histopathology, Kings College Hospital NHS Foundation Trust, London, UK
    • ,
  • D. Evans

      Affiliations

    • South East London Breast Screening Programme and National Breast Screening Training Centre, Kings College Hospital NHS, London, UK
    • ,
  • R. Wasan

      Affiliations

    • South East London Breast Screening Programme and National Breast Screening Training Centre, Kings College Hospital NHS, London, UK
    • ,
  • M.J. Michell

      Affiliations

    • South East London Breast Screening Programme and National Breast Screening Training Centre, Kings College Hospital NHS, London, UK

Received 8 March 2008 ,Revised 17 August 2008 ,Accepted 18 August 2008.

References 

  1. Stomper C, Geradts J, Edge S, et al. Mammographic predictors of the presence and size of invasive carcinomas associated with malignant microcalcification lesions without a mass. AJR Am J Roentgenol. 2003;181:1679–1684
  2. UK NHS Breast Screening Programme Statistics. Available from: http://www.cancerscreening.nhs.uk/breastscreen/statistics.html2005–2006
  3. Wahedna Y, Evans AJ, Pinder SE, et al. Mammographic size of ductal carcinoma in situ does not predict the presence of an invasive focus. Eur J Can. 2001;37:459–462
  4. Hoorntje LE, Schipper ME, Peeters PH, et al. The finding of invasive cancer after a preoperative diagnosis of ductal carcinoma-in-situ: causes of ductal carcinoma-in-situ underestimates with stereotactic 14-gauge needle biopsy. Ann Surg Oncol. 2003;10:748–753
  5. Yen TW, Hunt KK, Ross MI, et al. Predictors of invasive breast cancer in patients with an initial diagnosis of ductal carcinoma in situ: a guide to selective use of sentinel lymph node biopsy in management of ductal carcinoma in situ. J Am Coll Surg. 2005;200:516–526
  6. Evans AJ, Pinder SE, Ellis IO, et al. Screen detected ductal carcinoma in situ (DCIS): overdiagnosis or an obligate precursor of invasive disease?. J Med Screen. 2001;8:149–151
  7. Evans A, Blanks R. Should there be an upper limit for detection of ductal carcinoma in situ (DCIS) at mammographic screening? An analysis using using data from the UK NHS breast screening programme. Clin Radiol. 2002;57:1086–1089
  8. Jackman RJ, Nowels KW, Rodriguez-Soto J, Marzoni FA, et al. Stereotactic, automated, large-core needle biopsy of nonpalpable breast lesions: false-negative and histologic underestimation rates after long-term follow-up. Radiology. 1999;210:799–805
  9. Jackman RJ, Burbank F, Parker SH, et al. Stereotactic breast biopsy of nonpalpable lesions: determinants of ductal carcinoma in situ underestimation rates. Radiology. 2001;218:497–502
  10. Evans A. The diagnosis and management of pre-invasive breast disease. Breast Cancer Res. 2003;5:250–253
  11. Pathology report of breast disease. NHS Breast Screening Programme Publication no. 58, Available from: http://www.cancerscreening.nhs.uk/breastscreen/publications/nhsbsp58.html; January 2005.
  12. Bagnall JC, Evans AJ, Wilson RM, et al. Predicting invasion in mammographically detected microcalcification. Clin Radiol. 2001;56:828–832
  13. Goyal A, Douglas-Jones A, Monypenny I, et al. Is there a role of sentinel lymph node biopsy in ductal carcinoma in situ? Analysis of 587 cases. Breast Cancer Res Treat. 2006;98:311–314
  14. Dillon MF, McDermott EW, Quinn CM, et al. Predictors of invasive disease in breast cancer when core biopsy demonstrates DCIS only. J Surg Oncol. 2006;93:559–563
  15. Lagios M, Westdahl P, Margolin R, et al. Ductal carcinoma in situ. Relationship of extent of non-invasive disease to the frequency of occult invasion, multicentricity, lymph node metastases and short term treatment failures. Cancer. 1982;50:1309–1314
  16. Wilkie C, White L, Dupont E, et al. An update of sentinel lymph node mapping in patients with ductal carcinoma in situ. Am J Surg. 2005;190:563–566
  17. Renshaw AA. Predicting invasion in the excision specimen from breast core needle biopsy specimens with only ductal carcinoma in situ. Arch Pathol Lab Med. 2002;126:139–141
  18. Malik HZ, Wilkonson L, George AD, et al. Preoperative mammographic features predict clinicopathological risk factors for the development of local recurrence in breast cancer. Breast. 2000;9:329–333
  19. James JJ, Evans AJ, Pinder SE, et al. Is the presence of mammographic comedo calcification really a prognostic factor for small screen-detected invasive breast cancers?. Clin Radiol. 2003;58:54–62

PII: S0009-9260(08)00364-4

doi: 10.1016/j.crad.2008.08.007

Clinical Radiology
Volume 64, Issue 2 , Pages 178-183 , February 2009

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