Clinical Radiology
Volume 64, Issue 1 , Pages 12-21, January 2009

Magnetic resonance spectroscopy of the brain: review of metabolites and clinical applications

  • D.P. Soares

      Affiliations

    • Section of Radiology, Department of Surgery, Radiology, Anaesthetics, and Intensive Care, University Hospital of the West Indies, Mona, Kingston, Jamaica
    • Corresponding Author InformationGuarantor and correspondent: D. P. Soares, Section of Radiology, Department of Surgery, Radiology, Anaesthetics and Intensive Care, University Hospital of the West Indies, Mona, Kingston 7, Jamaica. Tel./fax: +876 9775277/9271933.
    • ,
  • M. Law

      Affiliations

    • Department of Radiology and Neurosurgery, Mount Sinai Medical Centre, New York, New York

Received 10 January 2008; received in revised form 1 July 2008; accepted 8 July 2008.

Magnetic resonance imaging (MRI) provides anatomic images and morphometric characterization of disease, whereas magnetic resonance spectroscopy (MRS) provides metabolite/biochemical information about tissues non-invasively in vivo. MRS has been used clinically for more than two decades. The major applications of this advanced MRI tool are in the investigation of neurological and neurosurgical disorders. MRS has also been used in the evaluation of the prostate gland and muscle tissue, but these applications will not be addressed in this review. The aim of this review is to attempt to introduce the technique, review the metabolites and literature, as well as briefly describe our clinical experience.

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PII: S0009-9260(08)00271-7

doi:10.1016/j.crad.2008.07.002

Clinical Radiology
Volume 64, Issue 1 , Pages 12-21, January 2009

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