Clinical Radiology
Volume 63, Issue 7 , Pages 783-790 , July 2008

Dynamic CT of portal hypertensive gastropathy: significance of transient gastric perfusion defect sign

  • T.U. Kim

      Affiliations

    • Department of Diagnostic Radiology, Pusan National University Hospital, Pusan National University School of Medicine and Medical Research Institute, Pusan National University, Busan 602-739, Republic of Korea
  • ,
  • S. Kim

      Affiliations

    • Department of Diagnostic Radiology, Pusan National University Hospital, Pusan National University School of Medicine and Medical Research Institute, Pusan National University, Busan 602-739, Republic of Korea
    • Corresponding Author InformationGuarantor and correspondent: S. Kim, Department of Diagnostic Radiology, Pusan National University Hospital, Pusan National University School of Medicine, #1-10, Ami-Dong, Seo-gu, Busan 602-739, Republic of Korea. Tel.: +82 51 240 7354; fax: +82 51 240 7534.
  • ,
  • S.K. Woo

      Affiliations

    • Department of Diagnostic Radiology, Pusan National University Hospital, Pusan National University School of Medicine and Medical Research Institute, Pusan National University, Busan 602-739, Republic of Korea
  • ,
  • J.W. Lee

      Affiliations

    • Department of Diagnostic Radiology, Pusan National University Hospital, Pusan National University School of Medicine and Medical Research Institute, Pusan National University, Busan 602-739, Republic of Korea
  • ,
  • T.H. Lee

      Affiliations

    • Department of Diagnostic Radiology, Pusan National University Hospital, Pusan National University School of Medicine and Medical Research Institute, Pusan National University, Busan 602-739, Republic of Korea
  • ,
  • Y.J. Jeong

      Affiliations

    • Department of Diagnostic Radiology, Pusan National University Hospital, Pusan National University School of Medicine and Medical Research Institute, Pusan National University, Busan 602-739, Republic of Korea
  • ,
  • J. Heo

      Affiliations

    • Department of Gastrointestinal Internal Medicine, Pusan National University Hospital, Pusan National University School of Medicine and Medical Research Institute, Pusan National University, Busan 602-739, Republic of Korea

Received 19 November 2007 ,Revised 30 January 2008 ,Accepted 11 February 2008.

References 

  1. Burak KW, Lee SS, Beck PL. Portal hypertensive gastropathy and gastric antral vascular ectasia (GAVE) syndrome. Gut. 2001;49:866–872
  2. Primignani M, Carpinelli L, Preatoni P, et al. Natural history of portal hypertensive gastropathy in patients with liver cirrhosis. The New Italian Endoscopic Club for the study and treatment of esophageal varices (NIEC). Gastroenterology. 2000;119:181–187
  3. Burak KW, Beck PL. Diagnosis of portal hypertensive gastropathy. Curr Opin Gastroenterol. 2003;19:477–482
  4. Zoli M, Merkel C, Magalotti D, et al. Evaluation of a new endoscopic index to predict first bleeding from the upper gastrointestinal tract in patients with cirrhosis. Hepatology. 1996;24:1047–1052
  5. Panes J, Bordas JM, Pique JM, et al. Increased gastric mucosal perfusion in cirrhotic patients with portal hypertensive gastropathy. Gastroenterology. 1992;103:1875–1882
  6. Yoshikawa I, Murata I, Nakano S, et al. Effects of endoscopic variceal ligation on portal hypertensive gastropathy and gastric mucosal blood flow. Am J Gastroenterol. 1998;93:71–74
  7. Gupta R, Sawant P, Parameshwar RV, et al. Gastric mucosal blood flow and hepatic perfusion index in patients with portal hypertensive gastropathy. J Gastroenterol Hepatol. 1998;13:921–926
  8. Chang D, Levine MS, Ginsberg GG, et al. Portal hypertensive gastropathy: radiographic findings in eight patients. AJR Am J Roentgenol. 2000;175:1609–1612
  9. Ishihara K, Ishida R, Saito T, et al. Computed tomography features of portal hypertensive gastropathy. J Comput Assist Tomogr. 2004;28:832–835
  10. Spina GP, Arcidiacono R, Bosch J, et al. Gastric endoscopic features in portal hypertension: final report of a consensus conference, Milan, Italy, 19 September 1992. J Hepatol. 1994;21:461–467
  11. Sarin SK, Shahi HM, Jain M, et al. The natural history of portal hypertensive gastropathy: influence of variceal eradication. Am J Gastroenterol. 2000;95:2888–2893
  12. Panes J, Casadevall M, Fernandez M, et al. Gastric microcirculatory changes of portal hypertensive rats can be attenuated by long-term estrogen–progestagen treatment. Hepatology. 1994;20:1261–1270
  13. Ohta M, Hashizume M, Higashi H, et al. Portal and gastric mucosal haemodynamics in cirrhotic patients with portal-hypertensive gastropathy. Hepatology. 1994;20:1432–1436
  14. Mezawa S, Homma H, Ohta H, et al. Effect of transjugular intrahepatic portosystemic shunt formation on portal hypertensive gastropathy and gastric circulation. Am J Gastroenterol. 2001;96:1155–1159
  15. Hashizume M, Tanaka K, Inokuchi K. Morphology of gastric microcirculation in cirrhosis. Hepatology. 1983;3:1008–1012
  16. Tarnawski AS, Sarfeh IJ, Stachura J, et al. Microvascular abnormalities of the portal hypertensive gastric mucosa. Hepatology. 1988;8:1488–1494
  17. Sarin SK, Sreenivas DV, Lahoti D, et al. Factors influencing development of portal hypertensive gastropathy in patients with portal hypertension. Gastroenterology. 1992;102:994–999
  18. Spahr L, Villeneuve JP, Dufresne MP, et al. Gastric antral vascular ectasia in cirrhotic patients: absence of relation with portal hypertension. Gut. 1999;44:739–742
  19. Payen JL, Cales P, Voigt JJ, et al. Severe portal hypertensive gastropathy and antral vascular ectasia are distinct entities in patients with cirrhosis. Gastroenterology. 1995;108:138–144
  20. Nabavi DG, Cenic A, Craen RA, et al. CT assessment of cerebral perfusion: experimental validation and initial clinical experience. Radiology. 1999;213:141–149

PII: S0009-9260(08)00084-6

doi: 10.1016/j.crad.2008.02.003

Clinical Radiology
Volume 63, Issue 7 , Pages 783-790 , July 2008