Clinical Radiology
Volume 63, Issue 1 , Pages 92-96 , January 2008

“Fallen fragment sign” in Langerhans' cell histiocytosis

  • F. Alyas

      Affiliations

    • Department of Radiology, The Royal National Orthopaedic Hospital, Stanmore, Middlesex, UK
    • Corresponding Author InformationGuarantor and correspondent: F. Alyas, The Royal National Orthopaedic Hospital, RNOH Stanmore, Brockley Hill, Stanmore, Middlesex HA7 4LP, UK. Tel.: +44 20895 42300; fax: +44 20890 95281.
    • ,
  • R. Tirabosco

      Affiliations

    • Department of Histopathology, The Royal National Orthopaedic Hospital, Stanmore, Middlesex, UK
    • ,
  • S. Cannon

      Affiliations

    • Department of Orthopaedics, The Royal National Orthopaedic Hospital, Stanmore, Middlesex, UK
    • ,
  • A. Saifuddin

      Affiliations

    • Department of Radiology, The Royal National Orthopaedic Hospital, Stanmore, Middlesex, UK

References 

  1. Reynolds J. The ‘fallen fragment sign’ in the diagnosis of unicameral bone cysts. Radiology. 1969;92:949–953
  2. Struhl S, Edelson C, Pritzker H, et al. Solitary (unicameral) bone cyst.The fallen fragment sign revisited. Skeletal Radiol. 1989;18:261–265
  3. Lee JH, Reinus WR, Wilson AJ. Quantitative analysis of the plain radiographic appearance of unicameral bone cysts. Invest Radiol. 1999;34:28–37
  4. McGlynn FJ, Mickelson MR, El-Khoury GY. The fallen fragment sign in unicameral bone cyst. Clin Orthop Relat Res. 1981;156:157–159
  5. Killeen KL. The fallen fragment sign. Radiology. 1998;207:261–262
  6. Hoover KB, Rosenthal DI, Mankin H. Langerhans cell histiocytosis. Skeletal Radiol. 2007;36:95–104
  7. Stull MA, Kransdorf MJ, Devaney KO. Langerhans cell histiocytosis of bone. RadioGraphics. 1992;12:801–823
  8. David R, Oria RA, Kumar R, et al. Radiologic features of eosinophilic granuloma of bone. AJR Am J Roentgenol. 1989;153:1021–1026
  9. Hindman BW, Thomas RD, Young LW, et al. Langerhans cell histiocytosis: unusual skeletal manifestations observed in thirty-four cases. Skeletal Radiol. 1998;27:177–181
  10. Park JS, Ryu KN. Hemophilic pseudotumor involving the musculoskeletal system: spectrum of radiologic findings. AJR Am J Roentgenol. 2004;183:55–61
  11. Tuzun M, Hekimoglu B. CT findings in skeletal cystic echinococcosis. Acta Radiol. 2002;43:533–538
  12. Okada K, Yoshida S, Okane K, et al. Cystic fibrous dysplasia mimicking giant cell tumor: MRI appearance. Skeletal Radiol. 2000;29:45–48
  13. Mahnken AH, Nolte-Ernsting CC, Wildberger JE, et al. Aneurysmal bone cyst: value of MR imaging and conventional radiography. Eur Radiol. 2003;13:1118–1124
  14. Dorfman HD, Czerniak B. Giant cell lesions. In:  Dorfman HD,  Czerniak B editor. Bone tumors. St Louis: Mosby; 1998;p. 559–606
  15. Komiya S, Minamitani K, Sasaguri Y, et al. Simple bone cyst: treatment by trepanation and studies on bone resorptive factors in cyst fluid with a theory of its pathogenesis. Clin Orthop Relat Res. 1993;287:204–211
  16. White PG, Saunders L, Orr W, et al. Chondromyxoid fibroma. Skeletal Radiol. 1996;25:79–81
  17. Tordeur M, Wybier M, Laporte JL, et al. Button sequestrum in a case of localized langerhans cell histiocytosis of the ilium: case report. Can Assoc Radiol J. 2000;51:90–92
  18. De Schepper AM, Ramon F, Van Marck E. MR imaging of eosinophilic granuloma: report of 11 cases. Skeletal Radiol. 1993;22:163–166
  19. Margau R, Babyn P, Cole W, et al. MR imaging of simple bone cysts in children: not so simple. Pediatr Radiol. 2000;30:551–557

PII: S0009-9260(07)00317-0

doi: 10.1016/j.crad.2007.06.008

Clinical Radiology
Volume 63, Issue 1 , Pages 92-96 , January 2008

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