Multi-detector row CT coronary angiography in patients with cardiomyopathy – initial single-centre experience

Manghat, N.E.; Morgan-Hughes, G.J.; Shaw, S.R.; Broadley, A.J.; Gogola, L.; Marshall, A.J.; Roobottom, C.A.

doi:10.1016/j.crad.2007.01.014

« Previous Next »Clinical Radiology
Volume 62, Issue 7 , Pages 632-638, July 2007

Multi-detector row CT coronary angiography in patients with cardiomyopathy – initial single-centre experience

N.E. Manghat
- Departments of Clinical Radiology, Derriford Hospital, Plymouth
- Guarantor and correspondent: N.E. Manghat, Department of Clinical Radiology, Derriford Hospital, Derriford, Plymouth, Devon PL6 8DH, UK. Tel.: +44 01752 792186. fax: +44 01752 792185.
G.J. Morgan-Hughes
- Department of Cardiology, Derriford Hospital, Plymouth
S.R. Shaw
- Department of School of Mathematics and Statistics, University of Plymouth, Devon, UK
A.J. Broadley
- Department of Cardiology, Derriford Hospital, Plymouth
L. Gogola
- Department of Cardiology, Derriford Hospital, Plymouth
A.J. Marshall
- Department of Cardiology, Derriford Hospital, Plymouth
C.A. Roobottom
- Departments of Clinical Radiology, Derriford Hospital, Plymouth

Received 13 November 2006; received in revised form 3 January 2007; accepted 8 January 2007.

Aims

To evaluate the diagnostic accuracy of computed tomography (CT) in assessing haemodynamically significant coronary artery stenoses in patients with cardiomyopathy (CM).

Subjects and Methods

Eighteen patients with CM were approached to undergo CT coronary angiography to evaluate the use of this technique for investigating the presence of significant coronary artery disease (CAD), and also to compare the findings with catheter angiography.

Results

On a segment-by-segment analysis the sensitivity, specificity, positive and negative predictive values in the CM group were 66.7, 96.5, 40 and 98.8%, respectively, with 100% accuracy in “whole-patient terms”.

Conclusion

Non-invasive, 16-detector row CT coronary angiography in patients with presumed CM would seem to be a useful clinical tool for the exclusion of significant coronary artery disease. However, the presence of suboptimal contrast opacification in this patient group means that the implication of these results must be interpreted with caution.