Clinical Radiology
Volume 62, Issue 4 , Pages 314-323 , April 2007

Radiological appearances of appendicular osteosarcoma: a comprehensive pictorial review

  • S. Suresh

      Affiliations

    • Department of Radiology, The Royal National Orthopaedic Hospital NHS Trust, Stanmore, Middlesex, HA7 4LP, UK
  • ,
  • A. Saifuddin

      Affiliations

    • Department of Radiology, The Royal National Orthopaedic Hospital NHS Trust, Stanmore, Middlesex, HA7 4LP, UK
    • The Institute of Orthopaedics and Musculoskeletal Sciences, University College London, London, UK
    • The London Bone and Soft Tissue Tumour Unit, University College London, London, UK
    • Corresponding Author InformationGuarantor and correspondent: A. Saifuddin, Department of Radiology, The Royal National Orthopaedic Hospital, Brockley Hill, Stanmore HA7 4LP, UK. Tel.: +44 (0)20 8909 5443; fax: +44 (0)20 8954 0281.

Received 26 June 2006 ,Revised 31 October 2006 ,Accepted 8 November 2006.

References 

  1. Resnick D, Kyriakos M, Green way GD. Tumor like diseases of bone: imaging and pathology of specific lesions. In:  Resnick D editors. Diagnosis of bone and joint disorders. 3rd ed.. Philadelphia, PA: Saunders; 1995;p. 3662–3697
  2. Huvos AG. Osteogenic sarcoma. In: Bone tumours: diagnosis, treatment, and prognosis. Philadelphia, PA: Saunders; 1991;p. 85–156
  3. Saifuddin A. The accuracy of imaging in the local staging of appendicular osteosarcoma. Skeletal Radiol. 2002 Apr;31(4):191–201
  4. Dahlin DC, CoventryMB . Osteogenic sarcoma. A study of six hundred cases. J Bone Joint Surg Am. 1967 Jan;49(1):101–110
  5. Norton KI, Hermann G, Abdelwahab IF, et al. Epiphyseal involvement in osteosarcoma. Radiology. 1991 Sep;180(3):813–816
  6. Panuel M, Gentet JC, Scheiner C, et al. Physeal and epiphyseal extent of primary malignant bone tumors in childhood: correlation of preoperative MRI and the pathologic examination. Pediatr Radiol. 1993;23(6):421–424
  7. O'Flanagan SJ, Stack JP, Mc Gee HM, et al. Imaging of intramedullary tumour spread in osteosarcoma. A comparison of techniques. J Bone Joint Surg Br. 1991 Nov;73(6):998–1001
  8. Redmond OM, Stack JP, Dervan PA, et al. Osteosarcoma: use of MR imaging and MR spectroscopy in clinical decision making. Radiology. 1989 Sep;172(3):811–815
  9. Schima W, Amann G, Stiglbauer R, et al. Preoperative staging of osteosarcoma: efficacy of MR imaging in detecting joint involvement. AJR Am J Roentgenol. 1994 Nov;163(5):1171–1175
  10. Sundaram M, Totty WG, Kyriakos M, et al. Imaging findings in pseudocystic osteosarcoma. Am J Roentgenol. 2001 Mar;176(3):783–788
  11. Paget J. Lectures on surgical pathology. Philadelphia, Pa: Lindsay & Blackiston; 1854;p. 486
  12. Matsuno T, Unni KK, McLeod RA, et al. Telangiectatic osteogenic sarcoma. Cancer. 1976 Dec;38(6):2538–2547
  13. Farr GH, Huvos AG, Marcove RC, et al. Telangiectatic osteogenic sarcoma. A review of twenty-eight cases. Cancer. 1974 Oct;34(4):1150–1158
  14. Huvos AG, Rosen G, Bretsky SS, et al. Telangiectatic osteogenic sarcoma: a clinicopathologic study of 124 patients. Cancer. 1982 Apr 15;49(8):1679–1689
  15. Mervak TR, Unni KK, Pritchard DJ, et al. Telangiectatic osteosarcoma. Clin Orthop Relat Res. 1991 Sep;(270):135–139
  16. Bacci G, Pignatti G, Dallari D, et al. Primary chemotherapy and delayed surgery (neoadjuvant chemotherapy) for telangiectatic osteogenic sarcoma of the extremities. J Chemother. 1989 Jun;1(3):190–196
  17. Pignatti G, Bacci G, Picci P, et al. Telangiectatic osteogenic sarcoma of the extremities. Results in 17 patients treated with neoadjuvant chemotherapy. Clin Orthop Relat Res. 1991 Sep;(270):99–106
  18. Rosen G, Huvos AG, Marcove R, et al. Telangiectatic osteogenic sarcoma. Improved survival with combination chemotherapy. Clin Orthop Relat Res. 1986 Jun;(207):164–173
  19. Murphey MD, Robbin MR, McRae GA, et al. The many faces of osteosarcoma. RadioGraphics. 1997 Sep–Oct;17(5):1205–1231
  20. Vanel D, Tcheng S, Contesso G, et al. The radiological appearances of telangiectatic osteosarcoma. A study of 14 cases. Skeletal Radiol. 1987;16(3):196–200
  21. Murphey MD, wan Jaovisidha S, Temple HT, et al. Telangiectatic osteosarcoma: radiologic-pathologic comparison. Radiology. 2003 Nov;229(2):545–553
  22. Unni KK, Dahlin DC, McLeod RA, et al. Intraosseous well-differentiated Osteosarcoma. Cancer. 1977;40:1337–1347
  23. Andersen KJ, Sundaram M, Unni KK, et al. Imaging of low grade central Osteosarcoma of the long bones and pelvis. Skeletal Radiol. 2004;33:373–379
  24. Sim FH, Unni KK, Beabout JW, et al. Osteosarcoma with small cells simulating Ewing's tumor. J Bone Joint Surg Am. 1979 Mar;61(2):207–215
  25. Edeiken J, Raymond AK, Ayala AG, et al. Small-cell osteosarcoma. Skeletal Radiol. 1987;16(8):621–628
  26. Martin SE, Dwyer A, Kissane JM, et al. Small-cell osteosarcoma. Cancer. 1982;50(5):990–996
  27. Ayala AG, Ro JY, Raymond AK, et al. Small cell osteosarcoma. A clinicopathologic study of 27 cases. Cancer. 1989 Nov 15;64(10):2162–2173
  28. Bertoni F, Present D, Bacchini P, et al. The Istituto Rizzoli experience with small cell osteosarcoma. Cancer. 1989 Dec 15;64(12):2591–2599
  29. Bertoni F, Unni KK, McLeod RA, et al. Cancer 1985 Osteosarcoma resembling osteoblastoma. Cancer. 1985 Jan 15;55(2):416–426
  30. Tani T, Okada K, Shoji K, et al. Osteoblastoma-like osteosarcoma. Skeletal Radiol. 2000 Nov;29(11):656–659
  31. Bertoni F, Bacchini P, Donati D, et al. Osteoblastoma-like osteosarcoma. The Rizzoli Institute experience. Mod Pathol. 1993 Nov;6(6):707–716
  32. Abramovici L, Kenan S, Hytiroglou P, et al. Osteoblastoma-like osteosarcoma of the distal tibia. Skeletal Radiol. 2002 Mar;31(3):179–182[Epub 2002 Jan 23]
  33. Unni KK. Case report 214. Skeletal Radiol. 1982;9:129–131
  34. Pignatti G, Manfrini M, Picci P, et al. Rare localizations of osteosarcoma: the epiphyses and tarsus osseus. Chir Organi Mov. 1986 Jan-Mar;71(1):27–31
  35. Muscolo DL, Campaner G, Aponte-Tinao LA, et al. Epiphyseal primary location for osteosarcoma and Ewing sarcoma in patients with open physis. J Pediatr Orthop. 2003 Jul–Aug;23(4):542–545
  36. Unni KK, Dahlin DC, Beabout JW, et al. Parosteal osteogenic sarcoma. Cancer. 1976 May;37(5):2466–2475
  37. Kenan S, Abdelwahab IF, Klein MJ, et al. Lesions of juxtacortical origin (surface lesions of bone). Skeletal Radiol. 1993;22(5):337–357
  38. Raymond AK. Surface osteosarcoma. Clin Orthop. 1991;270:140–148
  39. Okada K, Frassica FJ, Sim FH, et al. Parosteal osteosarcoma. A clinicopathological study. J Bone Joint Surg Am. 1994 Mar;76(3):366–378
  40. Huvos AG. Juxtacortical osteogenic sarcoma. In: Bone tumours: diagnosis, treatment, and prognosis. Philadelphia, PA: Sauders; 1991;p. 157–178
  41. Schajowicz F, McGuire MH, Santini Araujo E, et al. Osteosarcomas arising on the surfaces of long bones. J Bone Joint Surg Am. 1988 Apr;70(4):555–564
  42. Campanacci M, Picci P, Gherlinzoni F, et al. Parosteal osteosarcoma. J Bone Joint Surg Br. 1984 May;66(3):313–321
  43. Levine E, De Smet AA, Huntrakoon M. Juxtacortical osteosarcoma: a radiologic and histologic spectrum. Skeletal Radiol. 1985;14(1):38–46
  44. Jelinek JS, Murphey MD, Kransdorf MJ, et al. Parosteal osteosarcoma: value of MR imaging and CT in the prediction of histologic grade. Radiology. 1996 Dec;201(3):837–842
  45. Wold LE, Unni KK, Beabout JW, et al. Dedifferentiated parosteal osteosarcoma. J Bone Joint Surg Am. 1984 Jan;66(1):53–59
  46. Van Ongeval C, Lateur L, Baert AL. Parosteal osteosarcoma. J Belge Radiol. 1993 Jun;76(3):173–175
  47. Ritts GD, Pritchard DJ, Unni KK, et al. Periosteal osteosarcoma. Clin Orthop Relat Res. 1987 Jun;(219):299–307
  48. deSantos LA, Murray JA, Finklestein JB, et al. The radiographic spectrum of periosteal osteosarcoma. Radiology. 1978 Apr;127(1):123–129
  49. Murphey MD, Jelinek JS, Temple HT, et al. Imaging of periosteal osteosarcoma: radiologic-pathologic comparison. Radiology. 2004 Oct;233(1):129–138
  50. Wold LE, Unni KK, Beaubout JW, et al. High-grade surface osteosarcomas. Am J Surg Pathol. 1984 Mar;8(3):181–186
  51. Mirra JM, Dodd L, Johnston W, et al. Case report 700: primary intracortical osteosarcoma of femur, sclerosing variant, grade 1 to 2 anaplasia. Skeletal Radiol. 1991;20(8):613–616
  52. Kyriakos M. Intracortical osteosarcoma. Cancer. 1980;46:2525–2533
  53. Vigorita VJ, Jones JK, Ghelman B, et al. Intracortical osteosarcoma. Am J Surg Pathol. 1984 Jan;8(1):65–71
  54. Picci P, Gherlinzoni F, Guerra A. Intracortical osteosarcoma: rare entity or early manifestation of classical osteosarcoma?. Skeletal Radiol. 1983;9(4):255–258
  55. Amstutz HC. Multiple osteogenic sarcomata–metastatic or multicentric? Report of two cases and review of literature. Cancer. 1969 Nov;24(5):923–931
  56. Jeffree GM, Price CH, Sissons HA. The metastatic patterns of osteosarcoma. Br J Cancer. 1975 Jul;32(1):87–107
  57. Hopper KD, Moser RP, Haseman DB, et al. Osteosarcomatosis. Radiology. 1990 Apr;175(1):233–239
  58. Parham DM, Pratt CB, Parvey LS, et al. Childhood multifocal osteosarcoma. Clinicopathologic and radiologic correlates. Cancer. 1985 Jun 1;55(11):2653–2658
  59. Fitzgerald RH, Dahlin DC, Sim FH. Multiple metachronous osteogenic sarcoma. Report of twelve cases with two long-term survivors. J Bone Joint Surg Am. 1973 Apr;55(3):595–605

PII: S0009-9260(06)00407-7

doi: 10.1016/j.crad.2006.11.002

Clinical Radiology
Volume 62, Issue 4 , Pages 314-323 , April 2007